AAT1

Symbol: AAT1
Name: Aspartate AminoTransferase 1
Entrez gene ID: 853755
Ensembl gene ID: YKL106W
Species: Yeast (Taxid: 4932)

Functional description:
Aat1p; Mitochondrial aspartate aminotransferase, catalyzes the conversion of oxaloacetate to aspartate in aspartate and asparagine biosynthesis [Source:SGD;Acc:S000001589] [Ensembl]

Observation:

Overexpression of AAT1 extends replicative lifespan by 25% and does not synergize with 0.5% glucose restriction [18381895].



Interventions:
  • AAT1 overexpression +25%

  • Assays: Replicative Lifespan
    Mean: +25

    Classification:
  • Aging-Suppressor
  • Positive Aging-Suppressor
  • DR-Essential


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • AAT1 (4932)
  • KLLA0F13640g (28985)
  • AGOS_ABL038W (33169)



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