rpn-12

Symbol: rpn-12
Entrez gene ID: 174786
Ensembl gene ID: ZK20.5
Species: Worm (Taxid: 6239)

Functional description:
Non-ATPase Subunit of the 19S proteosomal component ; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (By similarity). [UniProt]

Observation:

RNAi decreased lifespan of glp-1 mutant, but not of WT or daf-2 mutant.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • PSMD8 (9606)
  • PSMD8 (9598)
  • PSMD8 (9615)
  • PSMD8 (9913)
  • PSMD8 (9913)
  • Psmd8 (10090)
  • Psmd8 (10116)
  • zgc:86762 (7955)
  • Rpn12 (7227)
  • AgaP_AGAP002606 (7165)
  • rpn-12 (6239)
  • rpn12 (4896)
  • RPN12 (4932)
  • KLLA0D11374g (28985)
  • AGOS_AFR278W (33169)
  • GeneID:2676609 (148305)
  • NCU10067 (5141)
  • RPN12a (3702)
  • Os07g0435100 (4530)
  • PFC0520w (5833)



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