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Symbol: rpn-1 Entrez gene ID: 177455 Ensembl gene ID: T22D1.9 Species: Worm (Taxid: 6239) Functional description: Protein RPN-1; proteasome Regulatory Particle, Non-ATPase-like family member (rpn-1) [Source:RefSeq peptide;Acc:NP_501064] [Ensembl]; rpn-1 encodes a non-ATPase subunit of the 26S proteasome's 19S regulatory particle (RP) base subcomplex; rpn-1 activity is essential for embryonic, larval, and germline development; by homology, RPN-1 is predicted to function in unfolding and recognition of protein substrates and/or recycling of ubiquitin moieties during protein degradation. [WormBase] Observation: RNAi decreased lifespan of WT, daf-2 and glp-1 mutant. Assays: Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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