MTC4

Symbol: MTC4
Name: Maintenance of Telomere Capping 4
Entrez gene ID: 852557
Ensembl gene ID: YBR255W
Species: Yeast (Taxid: 4932)

Functional description:
Mtc4p; Protein of unknown function, required for normal growth rate at 15 degrees C; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; mtc4 is synthetically sick with cdc13-1 [Source:SGD;Acc:S000000459] [Ensembl]

Observation:

Deletion of SLM6 increases replicative lifespan by approximately 37% in BY4742 [16293764] as well as mean chronological lifespan 13 - 210% (13, 49, 52, 210) in diploid cells [21447998].



Interventions:
  • SLM6 deletion +13 to +210%

  • Assays: Replicative Lifespan
    Mean: +13 to +210

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • MTC4 (4932)
  • KLLA0D15807g (28985)



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