spg-7

Symbol: spg-7
Name: human SPG (spastic paraplegia) 7
Entrez gene ID: 171915
Ensembl gene ID: Y47G6A.10
Species: Worm (Taxid: 6239)

Functional description:
Protein SPG-7; human SPG (spastic paraplegia) family member (spg-7) [Source:RefSeq peptide;Acc:NP_491165] [Ensembl]

Observation:

RNA interference of spg-7 in adulthood results in a 23% increase in mean lifespan [17411345].



Interventions:
  • spg-7 RNAi 0 to +23%

  • Assays: Organismal Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene
  • No Age Effect


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • AFG3L2 (9606)
  • AFG3L2 (9598)
  • AFG3L2 (9615)
  • AFG3L2 (9913)
  • Afg3l2 (10090)
  • Afg3l2 (10116)
  • AFG3L2 (9031)
  • si:ch211-12e1.4 (7955)
  • CG6512 (7227)
  • AgaP_AGAP006949 (7165)
  • spg-7 (6239)
  • SPBC543.09 (4896)
  • YTA12 (4932)
  • KLLA0F13706g (28985)
  • AGOS_ABL041W (33169)
  • GeneID:2683361 (148305)
  • NCU01479 (5141)
  • ftsh3 (3702)
  • ftsh10 (3702)
  • Os05g0458400 (4530)
  • Os01g0842600 (4530)
  • PF11_0203 (5833)



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