pnc-1

Symbol: pnc-1
Name: Pyrazinamidase and NiCotinamidase 1
Alias: cog-3
Entrez gene ID: 176833
Ensembl gene ID: Y38C1AA.3
Species: Worm (Taxid: 6239)

Functional description:
Protein PNC-1; Pyrazinamidase and NiCotinamidase family member (pnc-1) [Source:RefSeq peptide;Acc:NP_499876] [Ensembl]

Observation:

pnc-1 knockdown by RNAi decreases maximum lifespan by 30%. Overexpression of pnc-1 increases adult survival under oxidative stress but does not extend the lifespan [17335870].



Interventions:
  • pnc-1 RNAi -30%
  • pnc-1 overexpression

  • Assays: Organismal Lifespan

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • CG31216 (7227)
  • AgaP_AGAP001435 (7165)
  • pnc-2 (6239)
  • pnc-1 (6239)
  • SPBC365.20c (4896)
  • PNC1 (4932)
  • KLLA0F22242g (28985)
  • AGOS_AFR466C (33169)
  • GeneID:2679961 (148305)
  • NCU00713 (5141)

  • Orthologs
  • PNC1 (4932)
  • PNC1 (4932)
  • PNC1 (4932)



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