Symbol: unc-76 Name: UNCoordinated Entrez gene ID: 180014 Ensembl gene ID: C01G10.11 Species: Worm (Taxid: 6239) Functional description: Protein UNC-76; UNCoordinated family member (unc-76) [Source:RefSeq peptide;Acc:NP_506712] [Ensembl]; unc-76 encodes a predicted coiled-coil protein that belongs to the FEZ (fasciculation and elongation protein; zygin/zeta-1) family of proteins; UNC-76 activity is required for normal axonal outgrowth and fasciculation and hence, normal locomotion; UNC-76 expression begins during embryogenesis and is present in all axons throughout development; UNC-76 localizes to both axons and cell bodies. [WormBase] Observation: unc-76(e911) allele extends male lifespan by about 50%, but has no effect on hermaphrodite lifespan [10747056]. unc-76 mutants are uncoordinated [4366476]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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