Symbol: TPK2 Name: Takashi's Protein Kinase 2 Alias: PKA2; YKR1; PKA3 Entrez gene ID: 855898 Ensembl gene ID: YPL203W Species: Yeast (Taxid: 4932) Functional description: Tpk2p; cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase [Source:SGD;Acc:S000006124] [Ensembl] Observation: Deletion of TPK2 in a tpk1 and tpk3 double mutant background decreases PKA activity and extends replicative lifespan by approximately 25% in SGY446 strain [11000115]. Interventions: Assays: Replicative Lifespan Classification: Aging Relevance Analysis/Source: Homologs Orthologs Note: TPK2 is only Positive Gerontogenein TPK1 and TPK3 double mutant background. Edit \ Update (Admin) | Delete |
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