Denigma

tpa-1

Symbol: tpa-1
Name: TPA (tetradecanoyl phorbol acetate) resistant
Entrez gene ID: 176825
Ensembl gene ID: B0545.1
Species: Worm (Taxid: 6239)

Functional description:
PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. [UniProt]

Observation:

RNA interference in adulthood extended mean lifespan by 28%.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • PRKCD (9606)
  • PRKCD (9615)
  • PRKCD (9913)
  • Prkcd (10090)
  • Prkcd (10116)
  • PRKCD (9031)
  • LOC100150844 (7955)
  • prkcd (7955)
  • Pkcdelta (7227)
  • tpa-1 (6239)



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