Denigma

tlf-1

Symbol: tlf-1
Name: TBP-Like Factor
Entrez gene ID: 172676
Ensembl gene ID: F39H11.2
Species: Worm (Taxid: 6239)

Functional description:
Protein TLF-1; TBP-Like Factor family member (tlf-1) [Source:RefSeq peptide;Acc:NP_492356] [Ensembl]; The tlf-1 gene encodes a TATA binding protein (TBP)-like factor (TLF-1); TLF-1 is a functional transcriptional factor, and is required in vivo for zygotic embryonic RNA polymerase II transcription. [WormBase]

Observation:

RNA interference decreased median lifespan by 33% in wild type animals and 49% in daf-2 mutants.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • TBPL1 (9606)
  • TBPL1 (9598)
  • LOC476209 (9615)
  • LOC609509 (9615)
  • TBPL1 (9913)
  • Tbpl1 (10090)
  • Tbpl1 (10116)
  • TBPL1 (9031)
  • tbpl1 (7955)
  • AgaP_AGAP007517 (7165)
  • AgaP_AGAP000335 (7165)
  • tlf-1 (6239)



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