Denigma: Factor

Surf1

Symbol: Surf1
Name: surfeit gene 1
Entrez gene ID: 44498
Ensembl gene ID: FBgn0029117
Species: Fly (Taxid: 7227)

Functional description:
A putative COX assembly factor; Probably involved in the biogenesis of the COX complex (By similarity). [UniProt]

Observation:

Surf1 knockdown results in larval lethality. However, knockdown in the central nervous system (CNS) not only bypasses the larval lethality but it results in an increase in maximum lifespan of about 20-30% [16172499].

Assays: Organismal Lifespan
Maximum: +20 to +30

Classification:

Gerontogene

Positive Gerontogene

Type:

Gene

Protein coding

References:

16172499: Post-transcriptional silencing and functional characterization of the Drosophila melanogaster homolog of human Surf1.

Aging Relevance Analysis/Source:

GenAge