SNF4

Symbol: SNF4
Name: Sucrose NonFermenting 4
Entrez gene ID: 852763
Ensembl gene ID: YGL115W
Species: Yeast (Taxid: 4932)

Functional description:
Snf4p; Activating gamma subunit of the AMP-activated Snf1p kinase complex (contains Snf1p and a Sip1p/Sip2p/Gal83p family member); activates glucose-repressed genes, represses glucose-induced genes; role in sporulation, and peroxisome biogenesis [Source:SGD;Acc:S000003083] [Ensembl]

Observation:

Deleting SNF4 extends replicative lifespan by 10-20% in S288C strain [10921902].



Interventions:
  • SNF4 deletion +10 t +20%

  • Assays: Replicative Lifespan

    Classification:
  • Gerontogene
  • Negative Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • LOC475546 (9615)
  • zgc:153329 (7955)
  • SPAC1F12.01c (4896)
  • SNF4 (4932)
  • KLLA0F10769g (28985)
  • AGOS_AFL015C (33169)
  • GeneID:2677275 (148305)
  • NCU01471 (5141)
  • SNF4 (3702)
  • Os03g0856400 (4530)



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