Symbol: ROM2 Name: RhO1 Multicopy suppressor 2 Entrez gene ID: 851086 Ensembl gene ID: YLR371W Species: Yeast (Taxid: 4932) Functional description: Rom2p; GDP/GTP exchange factor (GEF) for Rho1p and Rho2p; mutations are synthetically lethal with mutations in rom1, which also encodes a GEF [Source:SGD;Acc:S000004363] [Ensembl] Observation: Deletion of ROM2 increases mean replicative lifespan of the alpha strain by about 50% [16293764]. ROM deletion mutant replicative lifespan increases by 49% in the alpha strain and 16% in a strain. Deletion of ROM2 increases replicative lifespan by 38% in the alpha strain and by 29.3% in the a strain (34.2% in both) [19030232]. Interventions: Assays: Replicative Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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