Symbol: rho-7 Name: rhomboid-7 Entrez gene ID: 36281 Ensembl gene ID: FBgn0033672 Species: Fly (Taxid: 7227) Functional description: Required for mitochondrial fusion during fly spermatogenesis and muscle maturation; rhomboid-7; rhomboid-7 [Source:FlyBase gene name;Acc:FBgn0033672] [Ensembl]; The gene rhomboid-7 is referred to in FlyBase by the symbol Dmel\rho-7 (CG8972, FBgn0033672). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: serine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process: mitochondrial fusion. 6 alleles are reported. The phenotypes of these alleles are annotated with: rhabdomere; Nebenkern; testis; eye photoreceptor cell; mitochondrion; seminal vesicle; indirect flight muscle; spermatozoon. It has one annotated transcript and one annotated polypeptide. Protein features are: Peptidase S54, rhomboid; Peptidase S54, rhomboid domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed in adult male stages. [FlyBase] Observation: rho-7 knockout flies have severe neurological defects and a much reduced lifespan [16713954]. Interventions: Assays: Organismal Lifespan Classification: Type: References: Aging Relevance Analysis/Source: Homologs Inparanoids Edit \ Update (Admin) | Delete |
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