Denigma

REI1

Symbol: REI1
Name: Cytoplasmic pre-60S factor
Alias: REquired for Isotropic bud growth 1
Entrez gene ID: 852569
Ensembl gene ID: YBR267W
Species: Yeast (Taxid: 4932)

Functional description:
Rei1p; Cytoplasmic pre-60S factor; required for the correct recycling of shuttling factors Alb1, Arx1 and Tif6 at the end of the ribosomal large subunit biogenesis; involved in bud growth in the mitotic signaling network [Source:SGD;Acc:S000000471] [Ensembl]

Observation:

REI1 deletion increases mean replicative lifespan by about 40% [16293764] in the alpha and a strains [19030232].



Interventions:
  • REI deletion +40%

    • Assays: Replicative Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • ZNF622 (9606)
  • ZNF622 (9615)
  • ZNF622 (9913)
  • Zfp622 (10090)
  • Znf622 (10116)
  • ZNF622 (9031)
  • znf622 (7955)
  • CG6769 (7227)
  • AgaP_AGAP002118 (7165)
  • C16A3.4 (6239)
  • SPCC550.15c (4896)
  • REI1 (4932)
  • KLLA0F01727g (28985)
  • AGOS_AEL165C (33169)
  • GeneID:2681602 (148305)
  • NCU04022 (5141)
  • AT4G31420 (3702)
  • FZF (3702)
  • Os06g0693500 (4530)



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