Denigma

Rae1

Symbol: Rae1
Name: RAE1 RNA export 1 homolog (S. pombe)
Entrez gene ID: 66679
Ensembl gene ID: ENSMUSG00000027509
Species: Mouse (Taxid: 10090)

Functional description:
Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton (By similarity). [UniProt]

Observation:

Haploinsufficiency of Bub3 and Rae1, but not haploinsufficiency of either gene by itself, reduces lifespan by 12% and appears to accelerate ageing.



Assays: Organismal Lifespan

Classification:
  • Aging Associated


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • RAE1 (9606)
  • RAE1 (9615)
  • RAE1 (9913)
  • Rae1 (10090)
  • Rae1 (10116)
  • rae1 (7955)
  • Rae1 (7227)
  • AgaP_AGAP012373 (7165)
  • npp-17 (6239)
  • rae1 (4896)
  • GLE2 (4932)
  • KLLA0E20703g (28985)
  • AGOS_AGL301C (33169)
  • GeneID:2674766 (148305)
  • NCU04288 (5141)
  • AT1G80670 (3702)
  • Os01g0635400 (4530)
  • Os08g0176800 (4530)

    • Inparanoids
  • ENSMUSP00000029013 (10090)
  • ENSRNOP00000029085 (10116)
  • YER107C (4932)
  • SPBC16A3.05c (4896)
  • ENSMUSP00000029013 (10090)
  • ENSMUSP00000029013 (10090)
  • ENSMUSP00000029013 (10090)



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