Denigma

R11A5.4

Symbol: R11A5.4
Name: R11A5.4b
Entrez gene ID: 172556
Ensembl gene ID: R11A5.4
Species: Worm (Taxid: 6239)

Functional description:
Protein PCK-2; Protein R11A5.4, isoform a [Source:UniProtKB/TrEMBL;Acc:O02286] [Ensembl]; R11A5.4 is one of three C. elegans genes that encode proteins with similarity to phosphoenolpyruvate carboxykinase (PEPCK); by similarity, the products of R11A5.4 are predicted to function in gluconeogenesis. [WormBase]

Observation:

RNA interference increased mean lifespan by 11% in daf-2 mutants but had no significant effect on wild type animals.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • PCK2 (9606)
  • PCK2 (9598)
  • PCK2 (9615)
  • PCK2 (9913)
  • Pck2 (10090)
  • Pck2 (10116)
  • pck2 (7955)
  • Pepck (7227)
  • AgaP_AGAP003350 (7165)
  • R11A5.4 (6239)
  • W05G11.6 (6239)



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