pat-6

Symbol: pat-6
Name: Paralysed Arrest at Two-fold
Entrez gene ID: 176848
Ensembl gene ID: T21D12.4
Species: Worm (Taxid: 6239)

Functional description:
Muscle assembly and function; Involved in the regulation of cell adhesion and cytoskeleton organization. Required to recruit unc-89 and myofilaments to newly forming attachments, and also to reposition the attachments so that they form the highly ordered array of dense body and M-line attachments that are characteristic of mature muscle cells. [UniProt]

Observation:

RNA interference increased mean lifespan by 13-21%.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • PARVB (9606)
  • PARVB (9615)
  • PARVB (9913)
  • Parvb (10090)
  • Parvb (10116)
  • PARVB (9031)
  • parvb (7955)
  • CG32528 (7227)
  • AgaP_AGAP002356 (7165)
  • pat-6 (6239)



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