Denigma

nac-2

Symbol: nac-2
Name: NADC (Na+-coupled dicarboxylate transporter) family
Entrez gene ID: 187898
Ensembl gene ID: R107.1
Species: Worm (Taxid: 6239)

Functional description:
High-affinity sodium-dicarboxylate cotransporter that accepts a range of tricarboxylic acid-cycle intermediates with 4-5 carbon atoms. There is no interaction with monocarboxylates (By similarity). [UniProt]

Observation:

RNA interference knockdown leads to an increase in average (19%) and maximal lifespan (50%).



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • SLC13A3 (9606)
  • SLC13A3 (9598)
  • SLC13A3 (9615)
  • SLC13A3 (9913)
  • Slc13a3 (10090)
  • Slc13a3 (10116)
  • slc13a3 (7955)
  • nac-2 (6239)
  • B0285.6 (6239)

    • Orthologs
  • Indy (7227)
  • Indy (7227)



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