mrs-1

Symbol: mrs-1
Name: Methionyl tRNA Synthetase
Entrez gene ID: 178089
Ensembl gene ID: F58B3.5
Species: Worm (Taxid: 6239)

Functional description:
Methionyl tRNA Synthetase; Protein MARS-1; Methionine--tRNA ligase, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q20970] [Ensembl]; mrs-1 encodes a predicted cytoplasmic methionyl-tRNA synthetase (MetRS), a class I aminoacyl-tRNA synthetase that catalyzes the attachment of methionine to its cognate tRNA and is thus required for protein biosynthesis; MRS-1 is essential for embryogenesis and required also for a normal rate of postembryonic growth. [WormBase]

Observation:

RNA interference increased mean lifespan by 23%.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • MARS (9606)
  • MARS (9598)
  • MARS (9615)
  • MARS (9913)
  • Mars (10090)
  • mars (7955)
  • CG15100 (7227)
  • AgaP_AGAP007891 (7165)
  • mrs-1 (6239)
  • rar1 (4896)
  • MES1 (4932)
  • KLLA0A09647g (28985)
  • AGOS_AGR332C (33169)
  • GeneID:2674746 (148305)
  • NCU07451 (5141)
  • AT4G13780 (3702)
  • Os06g0508700 (4530)



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