lbp-7

Symbol: lbp-7
Name: Lipid Binding Protein
Entrez gene ID: 191701
Ensembl gene ID: T22G5.2
Species: Worm (Taxid: 6239)

Functional description:
Protein LBP-7; Fatty acid-binding protein homolog 7 [Source:UniProtKB/Swiss-Prot;Acc:O02323] [Ensembl]; lbp-7 encodes a predicted intracellular fatty acid binding protein (iFABP) that is most similar to the vertebrate muscle and heart FABPs; by homology, LBP-7 is predicted to function as an intracellular transporter for small hydrophobic molecules such as lipids and steroid hormones; as loss of lbp-7 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of LBP-7 in C. elegans development and/or behavior is not yet known. [WormBase]

Observation:

RNA interference of lbp-7 resulted in a mean lifespan extension by about 14% in N2 rrf3(pk1426). lbp-7 is differentially transcribed in daf-16 and daf-2 RNAi animals [12845331].



Interventions:
  • lbp-7 RNAi +14%

  • Assays: Organismal Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • FABP4 (9606)
  • FABP4 (9598)
  • FABP4 (9913)
  • Fabp4 (10090)
  • Fabp4 (10116)
  • FABP4 (9031)
  • lbp-6 (6239)
  • lbp-8 (6239)
  • lbp-7 (6239)
  • lbp-5 (6239)



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