Symbol: KSS1 Name: Kinase Suppressor of Sst2 mutations 1 Entrez gene ID: 852931 Ensembl gene ID: YGR040W Species: Yeast (Taxid: 4932) Functional description: Proliferation, differentiation, transcription regulation and development; Kss1p; Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272] [Ensembl] Observation: Deletion of KSS1 results in increased sensitivity to heat shock and oxidative stress and a 25% reduction in median chronological lifespan [17662940]. Interventions: Assays: Chronological Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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