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Symbol: Irs2 Name: insulin receptor substrate 2 Entrez gene ID: 384783 Ensembl gene ID: ENSMUSG00000038894 Species: Mouse (Taxid: 10090) Functional description: Cytoplasmic signalling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines; May mediate the control of various cellular processes by insulin. [UniProt] Observation: Irs2 brain-specific knockout mice were overweight, hyperinsulinemic, glucose intolerant, yet more active and lived up to 18% longer. Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Orthologs Inparanoids Edit \ Update (Admin) | Delete |
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