Symbol: ife-1 Name: Initiation Factor 4E (eIF4E) family Entrez gene ID: 176755 Ensembl gene ID: F53A2.6 Species: Worm (Taxid: 6239) Functional description: A scaffold protein for translation initiation factors; disulfide bonds change the width and depth of the cap-binding cavity determining selectivity to mRNA caps. Required for progression through meiotic divisions during spermatogenesis and for the production of viable sperm. It is not required during oogenesis. [UniProt] Observation: RNA interference increased maximum lifespan by 7-10%. Assays: Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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