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Symbol: Hsp27 Name: Heat shock protein 27 Entrez gene ID: 39078 Ensembl gene ID: FBgn0001226 Species: Fly (Taxid: 7227) Functional description: Heat shock protein 27; Heat shock protein 27 [Source:FlyBase gene name;Acc:FBgn0001226] [Ensembl]; The gene Heat shock protein 27 is referred to in FlyBase by the symbol Dmel\Hsp27 (CG4466, FBgn0001226). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: defense response to fungus; determination of adult lifespan; defense response to bacterium. 19 alleles are reported. The phenotype of these alleles is annotated with: trichogen cell. It has one annotated transcript and one annotated polypeptide. Protein features are: Alpha crystallin/Heat shock protein; HSP20-like chaperone; Heat shock protein Hsp20. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of moderate expression. Peak expression observed during early pupal stages. [FlyBase] Observation: Overexpression of Hsp27 (by the UAS/GAL4 system) increases stress resistance and extends the mean lifespan by 30% [15308776]. Interventions: Assays: Organismal Lifespan Mean: +30 Classification: Type: References: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Orthologs Inparanoids Edit \ Update (Admin) | Delete |
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