hsp-16.48

Symbol: hsp-16.48
Name: Heat Shock Protein
Entrez gene ID: 179287
Ensembl gene ID: T27E4.3
Species: Worm (Taxid: 6239)

Functional description:
Protein HSP-16.48; Heat shock protein Hsp-16.48/Hsp-16.49 [Source:UniProtKB/Swiss-Prot;Acc:P02513] [Ensembl]

Observation:

Overexpression of the hsp-16 loci enhances stress resistance and extends mean lifespan by 11% at 20 degree Celsius. Lifespan extension by hsp-16 overexpression requires daf-16 [12882326]. RNAi of hsp-16.48 has no effect on adult wild-type lifespan but slightly shortens the long lifespan of age-1(hx546) mutants [14668486].



Interventions:
  • hsp-16 overexpression +11%
  • hsp-16.48 RNAi

  • Assays: Organismal Lifespan

    Classification:
  • Aging-Suppressor
  • Positive Aging-Suppressor


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • sip-1 (6239)
  • hsp-16.41 (6239)
  • hsp-16.49 (6239)
  • hsp-16.48 (6239)
  • F08H9.4 (6239)
  • hsp-16.11 (6239)
  • hsp-16.1 (6239)
  • F08H9.3 (6239)
  • hsp-16.2 (6239)

  • Orthologs
  • hsp-12.6 (6239)



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