glf-1

Symbol: glf-1
Name: GaLactoFuranose synthesis (UGM, UDP-galactopyranose mutase)
Entrez gene ID: 177358
Ensembl gene ID: H04M03.4
Species: Worm (Taxid: 6239)

Functional description:
Protein GLF-1; GaLactoFuranose synthesis (UGM, UDP-galactopyranose mutase) family member (glf-1) [Source:RefSeq peptide;Acc:NP_500884] [Ensembl]; glf-1 encodes a UDP-galactopyranose mutase predicted to synthesize galactofuranose (Gal(f)) as a nucleotide sugar (UDP-Gal(f)); recombinant GLF-1 has biochemical activity either in vivo (expressed in E. coli) or in vitro; orthologs of GLF-1 are found in the urochordates Halocynthia and Ciona. [WormBase]

Observation:

RNA interference decreased median lifespan by 49% in wild type animals, 76% in a daf-2 background and 33% in daf-2/daf-16 double mutants.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • glf-1 (6239)
  • GeneID:2684868 (148305)
  • NCU01824 (5141)



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