Denigma

gas-1

Symbol: gas-1
Name: General Anaesthetic Sensitivity abnormal
Entrez gene ID: 181646
Ensembl gene ID: K09A9.5
Species: Worm (Taxid: 6239)

Functional description:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). [UniProt]

Observation:

Mutation results hypersensitivity to volatile anesthetics and oxygen and reduced lifespan.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • NDUFS2 (9606)
  • NDUFS2 (9598)
  • NDUFS2 (9615)
  • NDUFS2 (9913)
  • Ndufs2 (10090)
  • Ndufs2 (10116)
  • ndufs2 (7955)
  • CG1970 (7227)
  • AgaP_AGAP006891 (7165)
  • AgaP_AGAP000794 (7165)
  • gas-1 (6239)
  • nduf-2.2 (6239)
  • GeneID:2680209 (148305)
  • NCU02534 (5141)
  • nad7 (3702)
  • nad7 (4530)



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