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Symbol: FIS1 Name: fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) Entrez gene ID: 854745 Ensembl gene ID: YIL065C Species: Yeast (Taxid: 4932) Functional description: Fis1p; Protein involved in mitochondrial membrane fission and peroxisome abundance; required for localization of Dnm1p and Mdv1p during mitochondrial division; mediates ethanol-induced apoptosis and ethanol-induced mitochondrial fragmentation [Source:SGD;Acc:S000001327] [Ensembl] Observation: Deletion of FIS1 prolongs significantly mean and maximum lifespan by 13 and 29% as well as improves the fitness of old mother cells (in BY4741) [17173038]. Interventions: Assays: Replicative Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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