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Symbol: fbp-1 Name: fructose-1,6-bisphosphatase Entrez gene ID: 266822 Ensembl gene ID: K07A3.1 Species: Worm (Taxid: 6239) Functional description: Protein FBP-1; Fructose-1,6-BiPhosphatase family member (fbp-1) [Source:RefSeq peptide;Acc:NP_491004] [Ensembl]; fbp-1 encodes fructose 1,6-bisphosphatase, a gluconeogenic enzyme that catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate in a reaction that reverses the third enzymatic step of glycolysis; FBP-1 is orthologous to human FBP1 (OMIM:229700, mutated in FBP deficiency). [WormBase] Observation: RNA interference extended mean lifespan by 10% in daf-2 mutants. Assays: Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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