F43G9.1

Symbol: F43G9.1
Entrez gene ID: 172655
Ensembl gene ID: F43G9.1
Species: Worm (Taxid: 6239)

Functional description:
Protein IDHA-1; SYmmetrical Sister cell hermaphrodite gonad defect family member (sys-1) [Source:RefSeq peptide;Acc:NP_492639] [Ensembl]; F43G9.1 encodes the C. elegans homolog of the alpha subunit of an NAD+-dependent mitochondrial isocitrate dehydrogenase; by homology, the product of F43G9.1 is predicted to catalyze the formation of alpha-ketoglutarate from isocitrate as part of the citric acid cycle. [WormBase]

Observation:

RNA interference extends lifespan.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • IDH3A (9606)
  • IDH3A (9598)
  • IDH3A (9615)
  • IDH3A (9913)
  • Idh3a (10090)
  • Idh3a (10116)
  • IDH3A (9031)
  • idh3a (7955)
  • l(1)G0156 (7227)
  • AgaP_AGAP002728 (7165)
  • F43G9.1 (6239)
  • idh2 (4896)
  • IDH2 (4932)
  • KLLA0E03125g (28985)
  • AGOS_AFR137C (33169)
  • GeneID:2679352 (148305)
  • NCU07697 (5141)
  • AT5G03290 (3702)
  • AT3G09810 (3702)
  • Os01g0276100 (4530)



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