SIRT3

Symbol: SIRT3
Name: sirtuin 3
Entrez gene ID: 23410
Ensembl gene ID: ENSG00000142082
Species: Human (Taxid: 9606)


Observation:

SIRT3 was found to be associated with longevity [14580859]. SIRT3 was found to be associated with longevity [15676284]. SIRT3 was found to be associated with longevity [15676284]. SIRT3 was found to be associated with longevity [19367319]. SIRT3 was found to be associated with longevity [19367319]. SIRT3 was not found to be associated with longevity [19367319]. SIRT3 was found to be associated with longevity [17989723]. SIRT3 was not found to be associated with longevity [23839864]. SIRT3 was found to be associated with longevity [23839864].



Assays: Organismal Lifespan

Longevity Associated Variants:
  • G477T 0.0272 [14580859]
  • VNTR in intron 5 (DeltaEF1 site) 8e-05 [15676284]
  • VNTR in intron 5 (GATA3 site) 0.025 [15676284]
  • many SNPs None [19367319]
  • rs939915 0.0145 [19367319]
  • - 0.145 [19367319]
  • rs3825075 1.0 [23839864]
  • rs4980329 0.02 [23839864]
  • rs11555236 0.03 [23839864]

  • Classification:
  • Longevity-Associated
  • No Age Effect


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • SIRT3 (9606)
  • SIRT3 (9615)
  • SIRT3 (9913)
  • Sirt3 (10090)
  • Sirt3 (10116)
  • SIRT3 (9031)
  • sirt3 (7955)
  • GeneID:2681820 (148305)

  • Orthologs
  • HST2 (4932)
  • HST2 (4932)
  • HST2 (4932)

  • Inparanoids
  • ENSMUSP00000026559 (10090)
  • ENSRNOP00000018861 (10116)
  • ENSMMUP00000011129 (9544)
  • YPL015C (4932)



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