Denigma

PPARG

Symbol: PPARG
Name: peroxisome proliferator-activated receptor gamma
Entrez gene ID: 5468
Ensembl gene ID: ENSG00000132170
Species: Human (Taxid: 9606)


Observation:

The Pro/Ala polyporphism in the PPARG gene at codon 12 was studied in 222 long-lived subjects and 250 aged subjects. A different genotype frequency was observed between long-lived and aged men; no differences were observed in the two age groups of women [15236769].PPARG was found to be associated with longevity [15236769]. PPARG was found to be associated with longevity [22985084].



Assays: Organismal Lifespan

Longevity Associated Variants:
  • rs1801282 0.035 [15236769]
  • rs1801282 0.03 [22985084]

    • Classification:
  • Longevity-Associated


    • Type:
  • Gene
  • Protein coding

    References:
  • 15236769: Gender specific association of genetic variation in peroxisome proliferator-activated receptor (PPAR)gamma-2 with longevity.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • PPARG (9606)
  • PPARG (9598)
  • PPARG (9615)
  • PPARG (9913)
  • Pparg (10090)
  • Pparg (10116)
  • PPARG (9031)
  • pparg (7955)

    • Inparanoids
  • ENSMUSP00000000450 (10090)
  • ENSRNOP00000012137 (10116)
  • ENSMMUP00000009427 (9544)



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