MTR

Symbol: MTR
Name: 5-methyltetrahydrofolate-homocysteine methyltransferase
Entrez gene ID: 4548
Ensembl gene ID: ENSG00000116984
Species: Human (Taxid: 9606)


Observation:

329 healthy individuals were examined for 2576A-->G (D919G) polymorphism in the MTR gene. Prevalence of the G-allele was significantly higher in the older than in the younger individuals. Separate analysis of female and male subjects revealed that the influence of the MTR genotype on male subjects became relevant at a younger age as opposed to female subjects suggesting a gender-dependent effect [16142417].



Assays: Organismal Lifespan

Classification:
  • Longevity-Associated


  • Type:
  • Gene
  • Protein coding

    References:
  • 16142417: The methionine synthase polymorphism c.2756Aright curved arrow G (D919G) is relevant for disease-free longevity.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • MTR (9606)
  • MTR (9598)
  • MTR (9615)
  • MTR (9913)
  • Mtr (10090)
  • Mtr (10116)
  • MTR (9031)
  • mtr (7955)
  • R03D7.1 (6239)



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