Symbol: IGF1R Name: insulin-like growth factor 1 receptor Entrez gene ID: 3480 Ensembl gene ID: ENSG00000140443 Species: Human (Taxid: 9606) Observation: The G/A, codon 1013 polymorphism was examined in healthy people 17-85 yr of age (n= 278; mean age, 54.8; 76 males and 202 females) and in healthy people 86-109 yr of age (n= 218; mean age, 98.0; 56 males and 162 females. The analysis revealed lower free IGF-I plasma levels in IGF1R A subjects (AG and AA genotypes) than in A- (GG genotype) subjects. A subjects were more represented among long-lived people than in young people [12843179].IGF1R was found to be associated with longevity [19489743]. IGF1R was found to be associated with longevity [12843179]. Assays: Organismal Lifespan Longevity Associated Variants: Classification: Type: References: Aging Relevance Analysis/Source: Homologs Orthologs Inparanoids Edit \ Update (Admin) | Delete |
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