Symbol: HMOX1 Name: heme oxygenase (decycling) 1 Entrez gene ID: 3162 Ensembl gene ID: ENSG00000100292 Species: Human (Taxid: 9606) Observation: A (GT)n repeat polymorphism in the promoter region of the human HO-1 gene was examined in younger (60 years, 59 male and 45 female) and older (60-75 years, 95 male and 106 female) subjects. The proportion of allelic frequencies in class L with a large size of (GT)n repeat, as well as the genotypic frequencies in group I with class L alleles, was significantly lower in the oldest male subjects than in the younger males. In contrast, in the oldest female subjects this was not observed [12566526].HMOX1 was found to be associated with longevity [12566526]. Assays: Organismal Lifespan Longevity Associated Variants: Classification: Type: References: Aging Relevance Analysis/Source: Homologs Inparanoids Edit \ Update (Admin) | Delete |
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