F7

Symbol: F7
Name: coagulation factor VII (serum prothrombin conversion accelerator)
Entrez gene ID: 2155
Ensembl gene ID: ENSG00000057593
Species: Human (Taxid: 9606)


Observation:

Blood coagulation factor VII (FVII) R/Q353 and FVII-323ins10 SNPs were examined in 187 centenarians (47 males and 140 females) and 201 controls (20-64 years). R/Q353 and FVII-323ins10 manifest significant influences on survival in males, with reduced hazards of death for carriers of the Q353 allele and the FVII-323P10 allele [11602206].F7 was found to be associated with longevity [15621215]. F7 was found to be associated with longevity [10744171]. F7 was found to be associated with longevity [10744171]. F7 was found to be associated with longevity [11602206].



Assays: Organismal Lifespan

Longevity Associated Variants:
  • rs201058276 0.01 [11602206]
  • 323ins10 0.01 [11602206]
  • R353Q 0.045 [15621215]

  • Classification:
  • Longevity-Associated


  • Type:
  • Gene
  • Protein coding

    References:
  • 11602206: Variations of cardiovascular disease associated genes exhibit sex-dependent influence on human longevity.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • F7 (9606)
  • F7 (9598)
  • F7 (9615)
  • F7 (9913)
  • LOC785517 (9913)
  • F7 (10090)
  • F7 (10116)
  • F7 (9031)
  • zgc:163025 (7955)

  • Inparanoids
  • ENSMUSP00000033820 (10090)
  • ENSRNOP00000038466 (10116)
  • ENSMMUP00000001388 (9544)



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