CPB2

Symbol: CPB2
Name: carboxypeptidase B2 (plasma)
Entrez gene ID: 1361
Ensembl gene ID: ENSG00000080618
Species: Human (Taxid: 9606)


Observation:

Genotypes of the CPB2 gene were studied in 2224 men and women aged 65 or older at baseline. During 10 years of follow-up, men with the -438 A/A genotype had decreased mortality due to all causes, and lived, on average, longer than men with the -438 G allele. The effects of -438 G/A in women were smaller and not statistically significant [15939070].CPB2 was found to be associated with longevity [15939070].



Assays: Organismal Lifespan

Classification:
  • Longevity-Associated


  • Type:
  • Gene
  • Protein coding

    References:
  • 15939070: Common promoter polymorphisms of inflammation and thrombosis genes and longevity in older adults: the cardiovascular health study.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • CPB2 (9606)
  • CPB2 (9598)
  • CPB2 (9615)
  • CPB2 (9913)
  • Cpb2 (10090)
  • Cpb2 (10116)
  • CPB2 (9031)
  • cpb2 (7955)
  • carboxypeptidase (6239)

  • Inparanoids
  • ENSMUSP00000022576 (10090)
  • ENSRNOP00000014909 (10116)
  • ENSMMUP00000022411 (9544)



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