Symbol: APOA1 Name: apolipoprotein A-I Entrez gene ID: 335 Ensembl gene ID: ENSG00000118137 Species: Human (Taxid: 9606) Observation: APOA1-MspI-RFLP (-75 nt from the transcription starting site) polymorphism was examined in a healthy population with 304 subjects aged 18-45 years, 267 subjects aged 46-80 years and 229 subjects aged 81-109 years (including 184 subjects, 43 males and 141 females, older than 100 years). The APOA1 allele P, which increases serum LDL-C at middle-age and is over-represented in cardiovascular diseases, tends to increase its frequency in the centenarians males [12556235].APOA1 was found to be associated with longevity [12556235]. Assays: Organismal Lifespan Longevity Associated Variants: Classification: Type: References: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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