Zw

Symbol: Zw
Name: Zwischenferment
Entrez gene ID: 32974
Ensembl gene ID: FBgn0004057
Species: Fly (Taxid: 7227)


Observation:

Mean lifespan of G6PD overexpressor flies is extended in comparison with driver and responder controls, armadillo-GAL4 (up to 38%), Tubulin-GAL4 (up to 29%), C23-GAL4 (up to 27%), da-GAL4 (up to 24%), D42-GAL4 (up to 18%) and Appl-GAL4 (up to 16%). The maximum lifespan is also increased [18809674].

G6PD enzymatic activity as well as levels of NADPH, NADH, and the GSH/GSSG ration are increased [18809674].



Interventions:
  • Zw overexpression +16 to + 38%

  • Assays: Organismal Lifespan

    Classification:
  • Aging-Suppressor
  • Positive Aging-Suppressor


  • Type:
  • Gene
  • Protein coding

    References:
  • 18809674: Overexpression of glucose-6-phosphate dehydrogenase extends the life span of Drosophila melanogaster.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • G6PD (9606)
  • G6PD (9615)
  • G6PD (9913)
  • G6pdx (10090)
  • G6pd (10116)
  • wu:fj78b06 (7955)
  • LOC100148915 (7955)
  • Zw (7227)
  • AgaP_AGAP010739 (7165)
  • AgaP_AGAP012678 (7165)
  • glucose-6-phosphate-1-dehydrogenase (6239)
  • zwf1 (4896)
  • ZWF1 (4932)
  • KLLA0D19855g (28985)
  • AGOS_ABL206C (33169)
  • GeneID:2680896 (148305)
  • NCU09111 (5141)
  • G6PD5 (3702)
  • G6PD6 (3702)
  • Os04g0485300 (4530)
  • Os02g0600400 (4530)
  • PF14_0511 (5833)

  • Inparanoids
  • FBpp0074517 (7227)
  • ENSMUSP00000004327 (10090)
  • ENSRNOP00000053157 (10116)
  • ENSMMUP00000022920 (9544)
  • ENSP00000358633 (9606)
  • YNL241C (4932)
  • SPAC3A12.18 (4896)



  • Edit \ Update (Admin) | Delete

    Comment on This Data Unit