Denigma

Pten

Symbol: Pten
Entrez gene ID: 43991
Ensembl gene ID: FBgn0026379
Species: Fly (Taxid: 7227)


Observation:

Increased Pten and 4E-BP activity in muscles is extends the lifespan [21111239].



Interventions:
  • Pten overexpression

    • Assays: Organismal Lifespan

    Classification:
  • Aging-Suppressor
  • Positive Aging-Suppressor


    • Type:
  • Gene
  • Protein coding

    References:
  • 21111239: FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • PTEN (9606)
  • PTEN (9598)
  • PTEN (9615)
  • PTEN (9913)
  • Pten (10090)
  • Pten (10116)
  • PTEN (9031)
  • ptenb (7955)
  • Pten (7227)
  • AgaP_AGAP009628 (7165)

    • Inparanoids
  • ENSMUSP00000013807 (10090)
  • ENSRNOP00000028143 (10116)
  • ENSMMUP00000011055 (9544)
  • ENSP00000361021 (9606)



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