elo-5

Symbol: elo-5
Name: fatty acid ELOngation
Entrez gene ID: 177320
Ensembl gene ID: F41H10.7
Species: Worm (Taxid: 6239)

Functional description:
Protein ELO-5; fatty acid ELOngation family member (elo-5) [Source:RefSeq peptide;Acc:NP_500793] [Ensembl]; The elo-5 gene encodes a paralog of elo-1 and elo-2, each of which encodes a polyunsaturated fatty acid (PUFA) elongase; ELO-5 is required for normally rapid growth and for normal fatty acid composition. In mass RNAi assays, elo-5(RNAi) animals grow abnormally slowly, and in individual assays, they display visibly altered fatty acid composition and multiple growth defects. [WormBase]

Observation:

RNA interference decreased median lifespan by 45% in wild type animals and 29% in daf-2 mutants.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • elo-1 (6239)
  • elo-5 (6239)
  • elo-6 (6239)
  • elo-7 (6239)
  • SUR4 (4932)
  • KLLA0B07777g (28985)
  • AGOS_AFR586W (33169)

  • Orthologs
  • SUR4 (4932)
  • SUR4 (4932)



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