Denigma: Factor

Srf

Symbol: Srf
Name: Serum Response Factor
Entrez gene ID: 20807
Ensembl gene ID: ENSMUSG00000015605
Species: Mouse (Taxid: 10090)

Observation:

SRF is activated by the daily variations of a blood signal, resulting in significant changes in the structure and size of live cells throughout the course of the day [23374345].

Daily variations of plasma signal cyclically stimulates SRF. SRF is solicited in an antiphasic manner in humans and rats, a fact that is linked to their activity, diurnal and nocturnal, respectively. SRF activation is accompanied by a remodeling of the cellular "skeleton", resulting in morphological change in cells based on their activity [23374345].

Assays: Organismal Lifespan

Classification:

Clock-Related

Circadian Differential

Transcription Factor

Type:

Gene

References:

23374345: Blood-Borne Circadian Signal Stimulates Daily Oscillations in Actin Dynamics and SRF Activity.

Aging Relevance Analysis/Source:

GenAge