2-ME

Symbol: 2-ME
Name: 2-Mercaptoethanol
Species: Mouse (Taxid: 10090)

Function:
Antioxidant

Observation:

Animals fed a diet supplemented with 2-mercaptoethanol (2-ME) exhibit an increased mean and maximum lifespan [6334792].

T-cell-dependent immune responses are higher in the 2-ME-fed mice compared to the controls when the animals are young. The accumulation of fluorescent products of lipid peroxidation damage is also delayed in the lymphocytes of the 2-ME-fed mice and tumor onset and incidence is reduced in these animals [6334792].



Interventions:
  • 2-ME treatment

  • Assays: Organismal Lifespan

    Classification:
  • Gero-Suppressant


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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