Denigma

icl-1

Symbol: icl-1
Name: IsoCitrate Lyase homolog 1
Alias: gei-7
Entrez gene ID: 178583
Ensembl gene ID: C05E4.9
Species: Worm (Taxid: 6239)


Observation:

RNAi knockdown of icl-1 (alias gei-7) starting at hatching or only during the adulthood significantly extends lifespan of wild-type, but does not alter, or even shortens the lifespan of eat-2 mutants [22810224].



Interventions:
  • icl-1 RNAi

    • Assays: Organismal Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene
  • DR-Essential


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • AgaP_AGAP005342 (7165)
  • gei-7 (6239)
  • DAL7 (4932)
  • MLS1 (4932)
  • GeneID:2682366 (148305)
  • NCU10007 (5141)
  • MLS (3702)



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