unc-6

Symbol: unc-6
Name: UNCoordinated 6
Entrez gene ID: 180961
Ensembl gene ID: F41C6.1
Species: Worm (Taxid: 6239)

Functional description:
Component of an extracellular matrix cue that guides dorsoventral migrations on the epidermis. Required for the guidance of pioneer axons and migrating cells along the body wall. Its association with either unc-40 or unc-5 receptors will lead to axon attraction or repulsion, respectively. [UniProt]

Observation:

Mutation in unc-6 has no effect on lifespan [9789046].

unc-6 mutants are uncoordinated [4366476].



Interventions:
  • unc-6 mutation

  • Assays: Organismal Lifespan

    Classification:
  • No Age Effect


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • NTN1 (9606)
  • NTN1 (9598)
  • NTN1 (9615)
  • NTN1 (9913)
  • Ntn1 (10090)
  • Ntn1 (10116)
  • NTN1 (9031)
  • ntn1a (7955)
  • NetB (7227)
  • unc-6 (6239)



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