STE12

Symbol: STE12
Name: STErile 12
Entrez gene ID: 856484
Ensembl gene ID: YHR084W
Species: Yeast (Taxid: 4932)

Functional description:
Ste12p; Transcription factor that is activated by a MAP kinase signaling cascade, activates genes involved in mating or pseudohyphal/invasive growth pathways; cooperates with Tec1p transcription factor to regulate genes specific for invasive growth [Source:SGD;Acc:S000001126] [Ensembl]

Observation:

Deletion of STE12 has no effect on replicative lifespan in strain PSY142 or BKY1-14c [7859289].

STE12 null mutants are sterile [6993497].



Interventions:
  • STE12 deletion

  • Assays: Replicative Lifespan

    Classification:
  • No Age Effect


  • References:
  • 7859289: Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • STE12 (4932)
  • KLLA0E17139g (28985)
  • AGOS_ADR304W (33169)



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