Denigma: Factor

RAD7

Symbol: RAD7
Name: RADiation sensitive 7
Entrez gene ID: 853512
Ensembl gene ID: YJR052W
Species: Yeast (Taxid: 4932)

Functional description:
Rad7p; Protein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad16p) during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex [Source:SGD;Acc:S000003813] [Ensembl]

Observation:

Deletion of RAD7 has no effect on replicative lifespan in PSY316 [10207108].

Mutation in RAD7 results in decrease repair of the non-transcribed strand in rDNA [8604332].

Interventions:

RAD7 deletion

Assays: Replicative Lifespan

Classification:

No Age Effect

Aging Relevance Analysis/Source:

GenAge