Denigma

hep

Symbol: hep
Name: hemipterous
Entrez gene ID: 32256
Ensembl gene ID: FBgn0010303
Species: Fly (Taxid: 7227)

Functional description:
bsk signal transduction pathway mediates an immune response and morphogenesis. [UniProt]

Observation:

Overexpression of hey significantly extends median (50%) and maximum (25%) lifespan. A hypomorphic allele of hep (hep1) laerlgy prevents lifespan extension caused by puc heterozygosity [14602080].



Interventions:
  • hep overexpression +50% +25%
  • hypomoprhic hep mutation

    • Assays: Organismal Lifespan

    Classification:
  • Aging-Suppressor
  • Positive Aging-Suppressor


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • MAP2K7 (9606)
  • MAP2K7 (9598)
  • MAP2K7 (9615)
  • MAP2K7 (9913)
  • Map2k7 (10090)
  • Map2k7 (10116)
  • si:ch211-254d18.2 (7955)
  • hep (7227)
  • AgaP_AGAP001867 (7165)
  • mek-1 (6239)



    • Edit \ Update (Admin) | Delete

    Comment on This Data Unit