dlk-1

Symbol: dlk-1
Name: DAP (Death Associated Protein kinase) Like Kinase
Entrez gene ID: 173128
Ensembl gene ID: F33E2.2
Species: Worm (Taxid: 6239)

Functional description:
Serine/threonine protein kinase; Component of a MAP kinase pathway that functions presynaptically to regulate synaptic architecture and presynaptic differentiation. Phosphorylates and activates mkk-4. [UniProt]

Observation:

Mutation reduced maximum lifespan by 30%.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • dlk-1 (6239)
  • HT1 (3702)
  • Os06g0636600 (4530)



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